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Business Summary: Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. It has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS. Its pipeline includes approximately 40 programs at various stages of discovery, pre-clinical and clinical development.
Financial Summary: BRIEF: For the fiscal year ended 31 December 2023, Sarepta Therapeutics Inc revenues increased 33% to $1.24B. Net loss decreased 24% to $536M. Revenues reflect Product, net increase of 36% to $1.14B, Collaboration and other increase of 10% to $98.5M. Lower net loss reflects Pharmaceutical segment loss decrease of 50% to $267.8M. Basic Earnings per Share excluding Extraordinary Items increased from -$8.03 to -$5.80.