Detail akcie Karyopharm Therap online

Business Summary: Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. It is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, oral SINE compound that, like selinexor, selectively blocks the nuclear export protein XPO1.
Financial Summary: BRIEF: For the fiscal year ended 31 December 2023, Karyopharm Therapeutics Inc revenues decreased 7% to $146M. Net loss decreased 13% to $143.1M. Revenues reflect Product revenue, net decrease of 7% to $112M, License and other revenue decrease of 7% to $34M. Lower net loss reflects Pharmaceutical segment loss decrease of 9% to $129.5M. Basic Earnings per Share excluding Extraordinary Items increased from -$2.02 to -$1.25.